THE EFFECTIVENESS OF THE STROMAL VASCULAR FRACTION IN RHEUMATOLOGICAL PATIENTS IN THE COMPLEX TREATMENT OF AVASCULAR NECROSIS OF THE FEMORAL HEAD

Abstract

Avascular necrosis of the femoral head (ANGBC) is a multifactorial disease affecting mainly young people, leading to the development of secondary severe osteoarthritis of the hip joints with subsequent disability (Lamb et al., 2019). The disease usually develops at the age of 35-55 years. There is no data on the prevalence of the disease in the general population. However, it has been noted that 10,000 to 50,000 new cases of the disease are diagnosed in the United States each year (Lafforgue, 2006). Only 20% of people develop ANGBC over the age of 50. The ratio of men and women is 3:1, half of the patients have bilateral lesions. Approximately 5-18% of all hip replacement surgeries are performed for primary angiosis (Nevskaya et al., 2017).

Avascular necrosis of the femoral head (ANGBC) is a multi - factorial disease that mainly affects young people, leading to the development of secondary severe osteoarthritis of the hip joints with subsequent disability (Lamb et al., 2019). The disease usually develops at the age of 35-55 years. Data on the prevalence of the disease in the general population are not provided. However, it has been noted that 10,000 to 50,000 new cases are diagnosed in the United States each year (Lafforgue, 2006). Only 20% of people with angioedema develop angioedema over the age of 50. The ratio of men to women is 3: 1, and half of the patients have a bilateral lesion. Approximately 5-18% of all эндопротезированиюhip replacement surgeries are performed for primary angioedema (Nevskaya et al., 2017).

Tadqiqot mavzusining dolzarbligi. Femur boshining avaskulyar nekrozi (AFH) ko'p omilli kasallik bo'lib, asosan yoshlarga ta'sir qiladi, bu esa keyingi nogironlik bilan birga son bo'g'imlarining ikkilamchi og'ir osteoartritining rivojlanishiga olib keladi (Lamb va boshq., 2019). Kasallik odatda 35 yoshdan 55 yoshgacha rivojlanadi. Umumiy aholi orasida kasallikning tarqalishi to'g'risida ma'lumotlar berilmagan. Shunga qaramay, har yili Qo'shma Shtatlarda kasallikning 10 000 dan 50 000 gacha yangi holatlari aniqlanishi qayd etilgan (Lafforgue, 2006). 50 yoshdan keyin odamlarning atigi 20 foizida ANFH rivojlanadi. Erkaklar va ayollar nisbati 3: 1, bemorlarning yarmida ikki tomonlama lezyonlar mavjud. Barcha kestirib, almashtirish operatsiyalarining taxminan 5-18% birlamchi ANFH uchun amalga oshiriladi (Nevskaya va boshq., 2017).